The following groups are active in the Pro-Cathedral parish:

Parish Pastoral Council

Parish Finance Committee

Society of Saint Vincent de Paul

Legion of Mary

Extraordinary Ministers of Holy Communion

Readers

Ministers of Welcome and Hospitality

Liturgical Assistants

Volunteer Cleaners

Church Collectors

Weekday Volunteers

Padre Pio Prayer Group

Palestrina Choir

Pro Nuova Music Group

Saint Mary's Pro-Cathedral Girls Choir

Crosscare

Daughters of Charity

Sisters of Our Lady of Sion

Blessed Sacrament Fathers

Central Model Junior School

Central Model Senior School

Scoil Chaoimhin Gaelscoil

Rotunda Hospital Chaplaincy

North City Centre Deanery

ILAC Centre Chapel